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Theses/Dissertations from 2024

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The Antioxidants and Anti-inflammatories Benefit of Broccoli Sprout Diets and Their Relation to Health, Tolu Esther Alaba

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Screen for Candida albicans Virulence Factors that Modulate the Host Immune Response in the Larval Zebrafish, Bailey A. Blair

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Native Frequency Domain Monte Carlo Simulation of Spatial Frequency Domain Imaging for Look-Up Table Generation, Daemon A. Dikeman

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Exploration of Liquid-infused Urinary Catheters: Fabrication, Functionality, and Liquid Loss, Chun Ki Fong

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There and Back Again: Creating, Characterizing, and Curing Murine Models of Rare Neuromuscular Disease, Sarah Holbrook

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Methionine Restriction Counteracts Age- and Diet-Related Metabolic Dysfunction in Mice, Marissa McGilvrey

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Understanding the Role of Fatty Acid Metabolism in Hematological Malignancies Through the Lens of the Acyl-COA Synthetase Long Chain Isozyme Family, Connor Murphy

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Mouse Genetic Approaches to Understand Neurological Phenotypes, George C. Murray

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Modeling the Innate Immune Response to Influenza a Virus Infection Using the Zebrafish, Brandy-Lee Soos

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Characterization of Adipose Tissue in Distinct Cardiovascular Disease Populations, Katie Stieber Ellis

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Notch Signaling Regulates Perivascular Adipose Tissue Functions, Chenhao Yang

Theses/Dissertations from 2023

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Investigation of Spatial Frequency Domain Imaging Analysis in Diabetic Foot Testing and Microneedle Treatments, Christian Crane

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Endothelial Interleukin-17 Receptor D (IL17RD) Promotes Western Diet-Induced Aortic Myeloid Cell Infiltration, Shivangi Pande

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Interactions Between Streptococcus agalactiae and Candida albicans Affect Persistence and Virulence, Kathryn Patenaude

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Exploring the Impact of PQN-75 and GLH-1/Vasa on Germline Development, Maintenance, and GSC Reprogramming Using Caenorhabditis elegans as a Model, Jesse D. Rochester

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On the Anti-adipogenic Function of Collagen Triple Helix Repeat-containing Protein 1, Matthew E. Siviski

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Rab27a as a Regulator of Thoracic Aorta Reactivity and Exosome Signaling, Ashley Soucy

Theses/Dissertations from 2022

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Primary Cilia of the Cardiac Neural Crest & Hedgehog-Mediated Mechanisms of Congenital Heart Disease, Lindsey A. Fitzsimons

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Genetic Determinants of Primary Nociceptor Sensitivity in Drosophila melanogaster, Christine Hale

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Immiscible Liquid-infused Filters for Water and Aerosol Filtration, Justin Hardcastle

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Telomerase Reverse Transcriptase Marks a Novel Population of Adult Stem Cells in the Mouse Brain That Respond to Metabolic Interventions by Modulating Adult Brain Plasticity, Gabriel S. Jensen

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Understanding the Contribution of Gα to the Yeast Pheromone Response, Cory Johnson

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Developing and Characterizing a Novel TEMPO CNF Hydrogel Adjuvant and Delivery System for Aquatic Vaccines, Kora Kukk

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Assessment of Cellular Alignment and Proliferation on Cellulose Nanofibril(CNF) Films, Sahar Roozbahani

Theses/Dissertations from 2021

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Nanocellulose Conduits for Enhanced Regeneration of Peripheral Nerve Injuries, Nicklaus R. Carter

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Krüppel-like Factor 9 Is a Feed-forward Regulator of Glucocorticoid Signaling, Ian Gans

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Translational Fidelity and its Role in Neuronal Homeostasis, Markus Terrey

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Manipulation of Particles and Fluid with Surface Acoustic Waves, Joel Scott Tewksbury

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Toward Improving Understanding of the Structure and Biophysics of Glycosaminoglycans, Elizabeth K. Whitmore

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Deciphering the Perpetual Fight Between Virus and Host: Utilizing Bioinformatics to Elucidate the Host's Genetic Mechanisms that Influence JC Polyomavirus Infection, Michael P. Wilczek

Theses/Dissertations from 2020

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Beyond the Brain: a Study of α-synuclein's Role in Bone and Adipose Tissue, Carolina A. Figueroa

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Zebrafish as a Model to Understand the Impact of Inactivity and Neuromuscular Electrical Stimulation on Duchenne Muscular Dystrophy, Elisabeth Kilroy

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Dissection of Molecular Mechanisms by Which Human Host Factors Regulate JC Polyomavirus Internalization, Colleen Mayberry

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Development, Design, and Utilization of a Reflective Based Photoplethysmography Sensor, Madeline Mazjanis

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Triclosan Disrupts Immune Cell Function by Depressing Ca2+ Influx via Acidification of the Cytoplasm, Suraj Sangroula

Theses/Dissertations from 2019

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Intravital Imaging in a Zebrafish Model Elucidates Interactions Between Mucosal Immunity and Pathogenic Fungi, Linda S. Archambault

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Neuromuscular Development and Phenotypic Variation in Zebrafish Models of Dystroglycanopathy, Erin Bailey

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The Importance of Brain-Adipose Communication for Metabolic Homeostasis, Magdalena Blaszkiewicz

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Characterization of ethanol-related phenotypic differences between C57BL/6J and C57BL/6NJ substrains: Role of Cyfip2?, Matthew C. Hartmann

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Exploring Different Peripheral Nociceptive Input Underlying Ongoing and Movement Evoked Cancer-Induced Bone Pain, Joshua Havelin

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Identification of Chromatin Regulators Perturbed in Hematopoietic Stem and Progenitor Cell Aging, Eraj S. Khokhar

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3D Printed Bioinspired Vascularized Polymers, Kayla Marquis

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Dynamic Regulation of G-Protein Signaling, William C. Simke

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Towards a Unified Disease Mechanism for tRNA Synthetase-Mediated Peripheral Neuropathy, Emily L. Spaulding

Theses/Dissertations from 2018

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Characterization of Phosphorylated G Protein Function and Membrane Culstering by Super Resolution Imaging, Sarah A. Alamer

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The Pathophysiological Role of Lyst Dysfunction in Retinal Pigment Epithelium, Xiaojie Ji

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Genetic Modification of Inherited Retinopathy in Mice, Yang Kong

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TARBP2 -Mediated Post-Transcriptional Regulation of Gene Expression During Murine Embryonic Development and Spermatogenesis, Sri Ramulu N. Pullagura

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Characterization and Functional Rescue of Congenital Muscular Dystrophy with Megaconial Myopathy in a Mouse Model of the Disease, Ambreen A. Sayed

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Host Mediated Mechanisms of Fungal Cell Spread in a Transparent Zebrafish Infection Model, Allison Scherer

Theses/Dissertations from 2017

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CGRP Effects on LP-BM5 Infection in Glial Cells, Eliza Grlickova-Duzevik

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Expression Profiling of Non-Coding RNA by Environmental Interactions in Innate Immunity, Jacob R. Longfellow

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The Role of IGFBP4 in Regulating Bone and Adipose Tissue Development in Mice, David Maridas

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Molecular and Pathological Analyses of Three New Mouse Mutations That Affect Ear Development and Function, Cong Tian

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Molecular Mechanisms Underlying Effects of Antibacterial Agent Triclosan on Cellular Signal Transduction and Mitochondrial Function, Lisa Weatherly

Theses/Dissertations from 2016

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Investigating the Effect of Particulate Hexavalent Chromium on Homologous Recombination Repair, Cynthia L. Browning

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Comparative Functional Genomic Analysis of Appendage and Heart Regeneration, Benjamin L. King

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Nucleocytoplasmic Transport Defects in Mouse Model of Amyotrophic Lateral Sclerosis, Tyler J. McGathey

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Effects of Opiates on Central Nervous System Immune Defense in Murine AIDS, Virginia D. McLane

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Investigating The Role of Orthopedia Homeobox in Prostate Epithelial Cell Cycle Regulation, Emmanuel Moses-Fynn

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Combinatorial Growth Factor Signaling Controls Nephron Progenitor Renewal and Differentiation, Sree Deepthi Muthukrishnan

Theses/Dissertations from 2015

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Defining the Role of the MicroRNA, MIR-101, IN Zebrafish Heart Regeneration, Megan JC Beauchemin

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Microengineering The Neural Tube, Christopher Demers

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Effects of Nutritional and Environmental Stress on Bone and Adipose Tissue in Mice, Casey Rae Doucette

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Cytokine and Epigenetic Regulation of MicroRNA in Acute Myeloid Leukemia, Amanda Jean Favreau

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Biomedical Engineering Research and Development on Addressing Urethral Incontinence and Bladder Irrigation, Mahdi Mohammadi

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The Role of Notch Signaling in Vascular Remodeling, Sarah Maier Peterson

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Mechanisms of DLL4/Notch and BMP9 Mediated Endothelial Cell Quiescence, Bahman Rostama

Theses/Dissertations from 2014

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Intersection of Renal Peritubular Cells, Mitogen Activated Kinases, and Chronic Kidney Disease, Justin Aurel Guay

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Developmental Cis-Regulatory Analysis of the Cyclin D Gene in the Sea Urchin Strongylocentrotus purpuratus, Christopher Michael McCarty

Theses/Dissertations from 2013

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Regulation of Vascular Smooth Muscle Phenotype by Notch Signaling, Joshua Michael Boucher

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Low-Dose Arsenic Exposure Alters Lipid Metabolism and Cell Cycle Regulation in Two Model Species, Danio rerio (Zebrafish) and Mus musculus (Mouse), Patrick Carlson

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The Role of Snail Family Genes During Mouse Long Bone Development, Ying Chen

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Role of Proprotein Convertases in HDL Metabolism, Seungbum Choi

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Exploring Mouse and Human Pluripotent Stem Cell Fate Determination with Bayesian Network Machine Learning, Karen Garvin Dowell

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Roles of Sprouty in Endothelial Cells During Angiogenesis, Yan Gong

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The Role of Sef (Similar Expression to FGF Genes) in Skeletal Development and Bone Homeostasis, Qing He

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Effects of Endocrine Disrupting Chemicals on Mast Cell Function, Rachel H. Kennedy

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Enabling Sum Frequency Spectroscopy and Fluorescence Correlation Spectroscopy of Model Cellular Membranes, Sarah M. Sterling

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Characterization of the Functional Role and Therapeutic Potential of microRNA miR-125a in Acute Myeloid Leukemia, Melanie Lorraine Ufkin

Theses/Dissertations from 2012

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Non-Invasive Imaging of Host Response in a Zebrafish Model of Candidemia, Kimberly Marie Brothers

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Cell-Matrix Adhesion in Muscle Development and Disease, Michelle F. Goody

Theses/Dissertations from 2011

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Roles of Matrix Metalloproteinase-11 and Tissue Inhibitor of Matrix Metalloproteinase-2B in Fibronectin Degradation During Zebrafish Development, Molly Harris Jenkins

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Developing Novel Opioid Analgesics for the Treatment of Acute and Chronic Pain, John J. Lowery

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Auditory Event-Related Potential in Neonates and Young Infants Prenatally Exposed to Methadone, Jonathan Allan Paul

Theses/Dissertations from 2009

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Spatial and Genetic Factors Influencing Yield in Lowbush Blueberry (Vaccinium angustifolium Mt.) in Maine, Daniel J. Bell

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Circadian Wheel-Running Activity During Withdrawal from Chronic Intermittent Ethanol Exposure in Mice, Ryan W. Logan