American Heart Association
We examined the hypothesis that lowered cognitive performance plays a role in the relation between elevated blood pressure and physical disability in performing basic physical tasks. A community-based sample (N = 1025) free from stroke and dementia (mean age: 61.1 years; SD: 13.0 years; 59.8% women) was used. Using path analysis, systolic and diastolic blood pressures (predictor variable) measured over multiple longitudinal examinations were averaged and related to multiple measures of cognition (intermediate variable) and physical ability (PA; outcome variable) measured at wave 6 of the Maine-Syracuse Study. PA was indexed by time required to execute standing, walking, and turning tests. A best-fit path model including blood pressure and multiple demographic and cardiovascular disease covariates was used. Paths from systolic blood pressure toglobal performance, verbal memory, andabstract reasoning (Similarities test) were significant (P
Elias, M. F., Dore, G. A., Davey, A., Robbins, M. A., & Elias, P. K. (2010). From blood pressure to physical disability: The role of cognition. Hypertension, 55, 1360-1365.
© 2010 American Heart Association, Inc.
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