Date of Award


Level of Access Assigned by Author

Campus-Only Thesis

Degree Name

Master of Science (MS)


Kinesiology and Physical Education


Robert A. Lehnhard

Second Committee Member

Stephen A. Butterfield

Third Committee Member

Kenneth McKeever


The purpose of this study was to determine the effects of rhuEPO administration on the immune response and hematological parameters in horses. Methods: Eight healthy, unconditioned mares were used for this study. Ages ranged from 4-10yrs, and weight from 450-500kg. The treatment group (n=4) received 50iu/kg bwt of rhuEPO (EPOGEN, Amgen, Inc., Thousand Oaks, California) in 3mL of saline 3 times/week for 3 weeks. The control group (n=4) received only the 3mL of saline on the same schedule. An ANOVA with repeated measures was used to determine any differences in immune response and hematological components between the two groups. Results: Significant (P